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Diabetes Drugs Help Body Handle Sugar
By Dave Kettner

Some people with may be able to control their blood glucose levels through diet and exercise however, the major will also require drugs to control the amount of sugar in their blood. Either is caused by the body not producing enough

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insulin to move the sugar from the blood into cells, where it is needed for energy, or the cells are not open to receive the sugar. In either event, the glucose is gathering in the blood with no way out and drugs can help it get through the system.

Persons with Type 2 are typically treated with oral medications, which are listed in five classifications. They are formulated to either increase the amount of insulin the body produces naturally, the effectiveness of how insulin works in the body or controls how the sugar is absorbed into the cells. Most drugs have few side effects, but all synthetic medications may create an adverse response in some patients and all side effects should be reported to the doctor.

One of the earliest drugs developed is sulfonylurea, developed to help the body produce more insulin. This class of drug has been in use since the mid-1900’s and has relatively few side effects.

Prompting Body To Use Available Insulin

Biguanides are a class of drugs usually prescribed to patients who are overweight. The most common brand name of this class of drug is Metformin and prompts the body to use the available insulin more effectively. These drugs have been known to cause nausea and diarrhea in some patients.  Alpha-glycosidase inhibitors slow the absorption of insulin into the digestive tract, giving it time to help glucose find its way into the body’s cells. Stomach and bowel problems are possible side effects of these drugs.

Controlling how the body deals with sugar following meals as the function of the meglitinide class of drugs. Often used for patients whose blood sugar levels increase dramatically following meals. This class of drugs has shown few side effects. Thiazolidinediones are developed to help make the body’s cells more sensitive to insulin, however the first batch of these drugs were suspected of causing livier damage in a few patients.

Newer formulations are believed to be much safer, but doctors continually monitor patients for potential liver damage. Doctors may begin patients on one or more of the drugs, and make adjustments throughout their treatment to help patients maintain a balanced blood glucose level.




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